1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 10
1.2 List of Figures 19
2 Introduction 20
2.1 Transdermal Drug Delivery Overview 20
3 Products under Development 21
3.1 Transdermal Drug Delivery – Pipeline Products by Stage of Development 21
3.2 Transdermal Drug Delivery – Pipeline Products by Segment 22
3.3 Transdermal Drug Delivery – Pipeline Products by Territory 23
3.4 Transdermal Drug Delivery – Pipeline Products by Regulatory Path 24
3.5 Transdermal Drug Delivery – Pipeline Products by Estimated Approval Date 25
3.6 Transdermal Drug Delivery – Ongoing Clinical Trials 26
4 Transdermal Drug Delivery – Pipeline Products under Development by Companies 27
4.1 Transdermal Drug Delivery Companies – Pipeline Products by Stage of Development 27
4.2 Transdermal Drug Delivery – Pipeline Products by Stage of Development 31
5 Transdermal Drug Delivery Companies and Product Overview 35
5.1 3M Company Company Overview 35
5.2 Aequus Pharmaceuticals Inc Company Overview 37
5.3 Agile Therapeutics Inc Company Overview 41
5.4 Allergan Plc Company Overview 47
5.5 Alliqua BioMedical Inc Company Overview 49
5.6 Altea Therapeutics Corporation (Inactive) Company Overview 51
5.7 Anterios Inc Company Overview 54
5.8 Apogee Technology Inc Company Overview 55
5.9 Avro Life Sciences Company Overview 56
5.10 Axxia Pharmaceuticals, LLC Company Overview 57
5.11 Burke Pharmaceuticals LLC Company Overview 58
5.12 Carbylan Therapeutics Inc Company Overview 60
5.13 Cerimon Pharmaceuticals, Inc. (Inactive) Company Overview 61
5.14 Corium International Inc Company Overview 62
5.15 DBV Technologies SA Company Overview 67
5.16 Dermisonics, Inc. Company Overview 69
5.17 Dharma Therapeutics, Inc. (Inactive) Company Overview 71
5.18 DURECT Corp Company Overview 72
5.19 Echo Therapeutics Inc Company Overview 74
5.20 Exploit Technologies Pte Ltd Company Overview 76
5.21 Extend Biosciences Inc Company Overview 77
5.22 EyeGate Pharmaceuticals Inc Company Overview 78
5.23 Fe3 Medical Inc Company Overview 83
5.24 FluGen Inc Company Overview 84
5.25 French National Institute of Health and Medical Research Company Overview 85
5.26 Hisamitsu Pharmaceutical Co Inc Company Overview 86
5.27 ImmuPatch Company Overview 93
5.28 Imperial College London Company Overview 95
5.29 Indian Institute of Technology Bombay Company Overview 96
5.30 Intercell AG (Inactive) Company Overview 97
5.31 Interstitial NS Company Overview 98
5.32 Isis Biopolymer, Inc. Company Overview 99
5.33 Janisys Company Overview 102
5.34 Massachusetts Institute of Technology Company Overview 103
5.35 Meda AB Company Overview 104
5.36 Medherant Ltd Company Overview 106
5.37 MEDRx Co., Ltd Company Overview 107
5.38 mesoestetic USA Inc Company Overview 112
5.39 Micropoint Technologies Pte Ltd Company Overview 113
5.40 National Taiwan Ocean University Company Overview 114
5.41 NeuroDerm Ltd Company Overview 115
5.42 Nitto Denko Corp Company Overview 122
5.43 North Carolina State University Company Overview 124
5.44 Novosanis NV Company Overview 126
5.45 Nuvo Pharmaceuticals Inc Company Overview 127
5.46 Old Dominion University Company Overview 129
5.47 Pantec Biosolutions AG Company Overview 130
5.48 Phosphagenics Ltd Company Overview 131
5.49 Purdue University Company Overview 135
5.50 Radius Health Inc Company Overview 136
5.51 Ratio Inc Company Overview 138
5.52 Scilex Ltd Company Overview 139
5.53 Sensile Medical AG Company Overview 140
5.54 Skinject Inc Company Overview 141
5.55 Solasia Pharma KK Company Overview 142
5.56 Sparsha Pharma International Pvt Ltd Company Overview 143
5.57 Sparsha Pharma USA Inc Company Overview 145
5.58 Stanford University Company Overview 146
5.59 Sumitomo Dainippon Pharma Co Ltd Company Overview 147
5.60 Syntropharma Ltd Company Overview 149
5.61 Teikoku Seiyaku Co Ltd Company Overview 150
5.62 tesa Labtec GmbH Company Overview 151
5.63 Teva Pharmaceutical Industries Ltd Company Overview 152
5.64 TheraJect Inc Company Overview 153
5.65 TheraSolve NV Company Overview 155
5.66 Theratech, Inc. Company Overview 157
5.67 Titan Pharmaceuticals Inc Company Overview 158
5.68 Transcu Group Limited (Inactive) Company Overview 161
5.69 Transdermal Delivery Solutions Corp Company Overview 162
5.70 TransPharma Medical Ltd Company Overview 163
5.71 Transport Pharmaceuticals Inc Company Overview 165
5.72 Univec, Inc. (Inactive) Company Overview 166
5.73 University of Illinois at Chicago Company Overview 169
5.74 University of Toronto Company Overview 170
5.75 Vyteris, Inc. (Inactive) Company Overview 171
5.76 Zambon Italia Srl Company Overview 172
5.77 Z-Cube Srl Company Overview 173
5.78 Zosano Pharma Corp Company Overview 174
5.79 Zynerba Pharmaceuticals Inc Company Overview 178
6 Transdermal Drug Delivery- Recent Developments 182
6.1 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 182
6.2 Nov 22, 2016: Innocoll Announces Third Quarter 2016 Financial and Operating Results and Provides Corporate Update 184
6.3 Nov 21, 2016: Corium Reports Fourth Quarter and Fiscal Year 2016 Financial Results and Recent Corporate Highlights 187
6.4 Nov 17, 2016: Aequus Prepares for Proof of Concept Clinical Study for Transdermal Anti-Nausea Diclegis Program 188
6.5 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 189
6.6 Nov 16, 2016: Nuvo Pharmaceuticals appoints new president 189
6.7 Nov 16, 2016: Nuvo Pharmaceuticals Appoints Jesse Ledger as President 190
6.8 Nov 15, 2016: Teva Reports Third Quarter 2016 Results 190
6.9 Nov 15, 2016: Cynosure Health Welcomes Three New Board Members 192
6.10 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 193
6.11 Nov 14, 2016: Adriane M. Brown to Join Allergan Board of Directors 193
6.12 Nov 11, 2016: Sumitomo Dainippon Pharma Announces Organizational Realignment and Changes Related to Officers and Other Key Positions 194
6.13 Nov 10, 2016: Phosphagenics Extends Due Diligence Period for Opioid Patches in Japan 196
6.14 Nov 10, 2016: Nuvo Pharmaceuticals Announces 2016 Third Quarter Results 196
6.15 Nov 10, 2016: Valeritas Reports Third Quarter 2016 Financial Results 198
6.16 Nov 09, 2016: Antares Pharma Reports Third Quarter 2016 Financial and Operating Results 199
6.17 Nov 09, 2016: Zosano Pharma Reports Third Quarter 2016 Financial Results 201
6.18 Nov 08, 2016: Teva Announces Appointment of New Chief Legal Officer 202
6.19 Nov 07, 2016: Agile Therapeutics Reports Third Quarter 2016 Financial Results 202
6.20 Nov 07, 2016: Camurus: Interim report January-September 2016 203
6.21 Nov 04, 2016: Alliqua BioMedical Reports Third Quarter and Nine-Months Fiscal Year 2016 Financial Results 204
6.22 Nov 03, 2016: Lannett Reports Fiscal 2017 First-Quarter Financial Results 206
6.23 Nov 03, 2016: Revance Releases Third Quarter 2016 Results 207
6.24 Nov 03, 2016: Radius Health Reports Third Quarter 2016 Financial and Operating Results 208
6.25 Nov 02, 2016: Allergan Reports Third Quarter 2016 Continuing Operations Performance with GAAP Net Revenues of $3.6 Billion; Announces Accelerated Share Repurchase, Initiation of Cash Dividend 211
6.26 Nov 02, 2016: EyeGate Pharmaceuticals Reports Third Quarter 2016 Financial Results and Provides Business Update 215
6.27 Nov 01, 2016: Cynosure Promotes Doug Delaney to Chief Commercial Officer 216
6.28 Oct 31, 2016: DURECT Announces Third Quarter 2016 Financial Results and Update of Programs 216
6.29 Oct 31, 2016: Antares Pharma Appoints Fred M. Powell, Senior Vice President and Chief Financial Officer 217
6.30 Oct 28, 2016: Probuphine Implant for Opioid Dependence Featured at 2016 International Society of Addiction Medicine Meeting 218
6.31 Oct 27, 2016: Probuphine Wins Popular Science’s “Best of What’s New” Award 219
6.32 Oct 26, 2016: Allergan Announces Changes to Board Leadership 219
6.33 Oct 26, 2016: GlaxoSmithKline: Results Announcement for the third quarter 2016 220
6.34 Oct 26, 2016: The Medicines Company Reports Third-Quarter 2016 Financial Results 226
6.35 Oct 25, 2016: Cynosure Announces Record Third-Quarter Revenues; Revenues Increase 36 Percent from Prior Year to $106.4 Million 227
6.36 Oct 25, 2016: Lilly Reports Third-Quarter 2016 Results 228
6.37 Oct 20, 2016: JDRF and the University of Toronto support research into a skin patch to prevent common, life-threatening risk of T1D 233
6.38 Oct 17, 2016: Aequus Advances Clinical Development of Transdermal Aripiprazole Patch 233
6.39 Oct 17, 2016: Hisamitsu America, the Global Leader of Topical Pain Patches, Introduces the Salonpas Lidocaine 4% Pain Relieving Gel-Patch 234
6.40 Oct 17, 2016: Zynerba Provides Clinical Update for Lead Development Candidate ZYN001 234
6.41 Oct 17, 2016: Braeburn Pharmaceuticals to Conduct Series of Probuphine (buprenorphine) Implant Trainings in Salt Lake City on October 27-29, 2016 for Qualified Healthcare Providers 235
6.42 Oct 05, 2016: Alliqua BioMedical Announces Preliminary Third Quarter of Fiscal Year 2016 Revenue 235
6.43 Oct 05, 2016: New Study Showcases Economic Impact of Allergan’s Operations on New Jersey Economy 236
6.44 Oct 05, 2016: Alliqua BioMedical Announces Preliminary Third Quarter of Fiscal Year 2016 Revenue; Earnings Conference Call Scheduled for November 4th 237
6.45 Oct 03, 2016: Noven Appoints Ralph Lipp, PH.D., as Vice President and Chief Scientific Officer 237
6.46 Sep 29, 2016: GlaxoSmithKline appoints Brian McNamara as CEO of GSK Consumer Healthcare 238
6.47 Sep 28, 2016: Edward D. Kobus, President of Invado Pharmaceuticals, Joins Transdermal Delivery Solutions Board of Advisors 238
6.48 Sep 27, 2016: Premier Biomedical Pain Management Solutions Announces Shipment of Initial Samples of Opioid-Free, 50-State Legal, Cannabis-Based Pain-Relieving Topical Patch 239
6.49 Sep 27, 2016: Medherant Raises USD2 Million in Venture Financing 239
6.50 Sep 22, 2016: Lannett Announces Resignation Of Mahendra Dedhiya, Ph.D., Chief Of Scientific Affairs 240
6.51 Sep 22, 2016: Industry Veteran Katherine D. Crothall, PhD to Join Valeritas Board of Directors 240
6.52 Sep 20, 2016: ALZYN Enters into Licensing Agreement with Transdermal Delivery Solutions 240
6.53 Sep 20, 2016: Emma Walmsley to succeed Andrew Witty as Chief Executive Officer of GlaxoSmithKline 241
6.54 Sep 19, 2016: NeuroDerm to Present ND0612H Data at 4th World Parkinson Congress 241
6.55 Sep 19, 2016: NeuroDerm to Present ND0612L Data at 4th World Parkinson Congress Demonstrating Ease of Use of Mini-Pump Delivery System 242
6.56 Sep 19, 2016: Radius Presents Abaloparatide Transdermal Patch Development Program at American Society for Bone and Mineral Research 2016 Annual Meeting 243
6.57 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 244
6.58 Sep 14, 2016: Levi Garraway, M.D., Ph.D., to become Senior Vice President of Global Oncology at Lilly, Succeeding Richard Gaynor, M.D., Who is Retiring after a Distinguished Career 245
6.59 Sep 13, 2016: Cynosure to Name Stephen J. Webber as New Chief Financial Officer 245
6.60 Sep 08, 2016: Chrono Therapeutics Raises USD47.6 Million in Series B Financing 246
6.61 Sep 08, 2016: Zosano Appoints Georgia Erbez as Chief Business Officer 246
6.62 Sep 07, 2016: Noven Announces Appointment of Jeff Mihm to its Board of Directors 246
6.63 Sep 06, 2016: Aequus Pharma Raises USD2 Million in Public Offering of Shares 247
6.64 Sep 01, 2016: Nuvo Pharmaceuticals Appoints New Chief Financial Officer 247
6.65 Aug 31, 2016: Jamere Jackson Elected To Lilly Board Of Directors 247
6.66 Aug 30, 2016: Aequus Provides Corporate Update on Commercial and Development Programs 248
6.67 Aug 25, 2016: Wallace K. Reams, Former President of Aveva Drug Delivery Systems Joins Transdermal Delivery Solutions Board of Advisors 250
6.68 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 250
6.69 Aug 24, 2016: Acrux: Financial Report for the year ended 30 June 2016 253
6.70 Aug 23, 2016: Lannett Announces Record Net Sales For Fiscal 2016 Fourth-Quarter And Full-Year 254
6.71 Aug 16, 2016: Valeritas Appoints Erick J. Lucera as Chief Financial Officer 255
6.72 Aug 12, 2016: Echo Therapeutics Announces Second Quarter 2016 Financial Results 255
6.73 Aug 10, 2016: EyeGate Pharmaceuticals Reports Second Quarter 2016 Financial Results and Provides Business Update 256
6.74 Aug 10, 2016: Lilly announces Joshua Smiley, Anat Ashkenazi appointed to new roles, Thomas Grein retires 257
6.75 Aug 10, 2016: Nuvo Pharmaceuticals Announces 2016 Second Quarter Results 258
6.76 Aug 10, 2016: Zosano Pharma Reports Second Quarter 2016 Financial Results 259
6.77 Aug 10, 2016: Valeritas Reports Second Quarter 2016 Financial Results 260
6.78 Aug 09, 2016: Alliqua BioMedical Reports Second Quarter and Six Months Fiscal Year 2016 Financial Results 261
6.79 Aug 09, 2016: Antares Pharma Reports Second Quarter 2016 Operating and Financial Results 263
6.80 Aug 09, 2016: EDA Board Acts to Encourage Global Pharmaceutical Company Allergan to Expand in New Jersey 264
6.81 Aug 08, 2016: Fe3 Medical Raises Additional USD3.5 Million in Series B Financing Round 265
6.82 Aug 08, 2016: Allergan Reports Strong Second Quarter 2016 Continuing Operations Performance with Net Revenues of $3.7 Billion 265
6.83 Aug 08, 2016: Agile Therapeutics Reports Second Quarter 2016 Financial Results 269
6.84 Aug 05, 2016: Aequus Announces Advancement of Anti-Nausea Transdermal Extended-Release Patent Application 270
6.85 Aug 04, 2016: Teva Reports Second Quarter 2016 Results 271
6.86 Aug 04, 2016: Radius Health Reports Second Quarter 2016 Financial and Operating Results 275
6.87 Aug 04, 2016: Revance Releases Second Quarter 2016 Results 277
6.88 Aug 04, 2016: Corium Reports Third Quarter Fiscal 2016 Financial Results and Recent Corporate Highlights 278
6.89 Aug 02, 2016: Braeburn Pharmaceuticals to Conduct First Series of Probuphine (buprenorphine) Implant Trainings in San Juan on August 5, 6 and 7 for Qualified Healthcare Providers 279
6.90 Aug 01, 2016: DURECT Announces Second Quarter 2016 Financial Results and Update of Programs 280
7 Appendix 416
7.1 Methodology 416
7.2 About GlobalData 419
7.3 Contact Us 419
7.4 Disclaimer 419